Journal of Dairy Science
Volume 89, Issue 6 , Pages 1951-1955 , June 2006

Factors Affecting Growth Factor Activity in Goat Milk

  • F.Y. Wu

      Affiliations

    • Animal Science Department, National Ilan University, Ilan 26047, Taiwan
    • Corresponding Author InformationCorresponding author.
    • ,
  • P.H. Tsao

      Affiliations

    • Animal Science Department, National Ilan University, Ilan 26047, Taiwan
    • ,
  • D.C. Wang

      Affiliations

    • Livestock Research Institute, Council of Agriculture, Hueng-Chun 94643, Taiwan
    • ,
  • S. Lin

      Affiliations

    • Animal Science Department, National Ilan University, Ilan 26047, Taiwan
    • ,
  • J. Wu

      Affiliations

    • Livestock Research Institute, Council of Agriculture, Hueng-Chun 94643, Taiwan
    • ,
  • Y.K. Cheng

      Affiliations

    • Livestock Research Institute, Council of Agriculture, Hueng-Chun 94643, Taiwan

Received 23 September 2005 ,Accepted 1 December 2005.

References 

  1. Ankrapp DP, Bennett JM, Haslam SZ. Role of epidermal growth factor in the acquisition of ovarian steroid hormone responsiveness in the normal mouse mammary gland. J. Cell. Physiol. 1998;174:251–260
  2. Brown CF, Teng CT, Pentecost BT, DiAugustine RP. Epidermal growth factor precursor in mouse lactating mammary gland alveolar cells. Mol. Endocrinol. 1989;3:1077–1083
  3. Brown KD, Blakeley DM. Partial purification and characterization of a growth factor present in goat's colostrum. Biochem. J. 1984;219:609–617
  4. Carpenter G. Epidermal growth factor is a major growth-promoting agent in human milk. Science. 1980;210:198–199
  5. Clarke MY, Brayer J, Heintz K, Nagashima H, Cha S, Oxford GE, et al. Differential absorption and distribution of epidermal growth factor and insulin-like growth factor in diabetic NOD mice. J. Diabetes Complicat. 2001;15:103–111
  6. Denhard M, Claus R, Munz O, Weiler U. Course of epidermal growth factor (EGF) and insulin-like growth factor I (IGF-I) in mammary secretions of the goat during end-pregnancy and early lactation. J. Vet. Med. Ser. A. 2000;47:533–540
  7. Droke EA, Paape MJ, Di Carlo AL. Prevalence of high somatic cell counts in bulk tank goat milk. J. Dairy Sci. 1993;76:1035–1039
  8. Gow CB, Moore GPM. Epidermal growth factor alters milk composition and fluid balance of lactating ewes. J. Endocrinol. 1992;132:377–385
  9. Grosvenor CE, Picciano MF, Baumrucker CR. Hormones and growth factors in milk. Endocr. Rev. 1992;14:710–728
  10. Knight CH, Peaker M. Mammary development and regression during lactation in goats in relation to milk secretion. Q. J. Exp. Physiol. 1984;69:331–338
  11. Koldovsky O. The potential physiological significance of milk-bone hormonally active substances for the neonate. J. Mammary Gland Biol. Neoplasia. 1996;1:317–323
  12. Konturek JW, Brzozowski T, Konturek SJ. Epidermal growth factor in protection, repair, and healing of gastroduodenal mucosa. J. Clin. Gastroenterol. 1991;13(Suppl. 1):S88–S97
  13. Li, S.C. 1578 (Ming dynasty). Pen Tsao Kang Mu (Compendium of Material Medica).
  14. Neville MC, McFadden TB, Forsyth I. Hormonal regulation of mammary differentiation and milk secretion. J. Mammary Gland Biol. Neoplasia. 2002;7:49–66
  15. Nishimura S, Maeno N, Matsuo K, Nakajima T, Kitajima I, Saito H, et al. Human lactiferous mammary gland cells produce vascular endothelial growth factor (VEGF) and express the VEGF receptors, Flt-1 and KDR/Flk-1. Cytokine. 2002;18:191–198
  16. Pitelka DR, Hamamoto ST, Duafala JG, Nemanic MK. Cell contacts in the mouse mammary gland. I. Normal gland in postnatal development and the secretory cycle. J. Cell Biol. 1973;56:797–818
  17. Playford RJ, Macdonald CE, Johnson WS. Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders. Am. J. Clin. Nutr. 2000;72:5–14
  18. Prosser C, Stelwagen K, Cummins R, Guerin P, Gill N, Milne C. Reduction of heat-induced gastrointestinal hyper-permeability in rats by bovine colostrum and goat milk powders. J. Appl. Physiol. 2004;96:650–654
  19. Puccio F, Lehy T. Oral administration of epidermal growth factor in suckling rats stimulates cell DNA synthesis in fundic and antral gastric mucosae as well as in intestinal mucosa and pancreas. Regul. Pept. 1988;20:53–64
  20. Purushotham KR, Offenmuller K, Bui AT, Zelles T, Blazsek J, Schultz GS, et al. Absorption of epidermal growth factor occurs through the gastrointestinal tract and oral cavity in adult rats. Am. J. Physiol. 1995;269:G867–G873
  21. SAS Institute. SAS/STAT User's Guide. Cary, NC: SAS Inst. Inc.; 1988;
  22. Shing YW, Klagsbrun M. Human and bovine milk contain different sets of growth factors. Endocrinology. 1984;115:273–282
  23. Stelwagen K, Davis SR, Farr VC, Prosser CG, Sherlock RA. Mammary epithelial cell tight junction integrity and mammary blood flow during an extended milking interval in goats. J. Dairy Sci. 1994;77:426–432
  24. Sung YY, Wu TI, Wang PH. Evaluation of milk quality of Alpine, Nubian, Saanen and Toggenburg breeds in Taiwan. Small Rumin. Res. 1999;33:17–23
  25. Sunil N, Bennett JM, Haslam SZ. Hepatocyte growth factor is required for progestin-induced epithelial proliferation and alveolar-like morphogenesis in serum-free culture of normal mammary epithelial cells. Endocrinology. 2002;143:2953–2960
  26. Wilson DJ, Stewart KN, Sears PM. Effects of stage of lactation, production, parity and season on somatic cell counts in infected and uninfected dairy goats. Small Rumin. Res. 1995;16:165–169
  27. Wu FY, Elsasser TH. Studies on cell growth promoting activity in goat milk. J. Chinese Agric. Chem. Society. 1995;33:326–332
  28. Yamada Y, Saito S, Morikawa H. Hepatocyte growth factor in human breast milk. Am. J. Reprod. Immunol. 1998;40:112–120
  29. Yang Y, Spitzer E, Meyer D, Sachs M, Niemann C, Hartmann G, et al. Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland. J. Cell Biol. 1995;131:215–226
  30. Zeng SS, Escobar EN. Effect of parity and milk production on somatic cell count, standard plate count and composition of goat milk. Small Rumin. Res. 1995;17:269–274

PII: S0022-0302(06)72262-7

doi: 10.3168/jds.S0022-0302(06)72262-7

Journal of Dairy Science
Volume 89, Issue 6 , Pages 1951-1955 , June 2006

Article Tools

* Image Usage & Resolution