Journal of Dairy Science
Volume 90, Issue 2 , Pages 541-546 , February 2007

Bovine α-Lactalbumin Stimulates Mucus Metabolism in Gastric Mucosa

  • Y. Ushida

      Affiliations

    • Biochemical Research Laboratory, Morinaga Milk Industry Co. Ltd., Zama, Kanagawa 228-8583, Japan
    • Corresponding Author InformationCorresponding author.
  • ,
  • Y. Shimokawa

      Affiliations

    • Biochemical Research Laboratory, Morinaga Milk Industry Co. Ltd., Zama, Kanagawa 228-8583, Japan
  • ,
  • T. Toida

      Affiliations

    • Biochemical Research Laboratory, Morinaga Milk Industry Co. Ltd., Zama, Kanagawa 228-8583, Japan
  • ,
  • H. Matsui

      Affiliations

    • Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan
  • ,
  • M. Takase

      Affiliations

    • Biochemical Research Laboratory, Morinaga Milk Industry Co. Ltd., Zama, Kanagawa 228-8583, Japan

Received 2 July 2006 ,Accepted 26 September 2006.

  • Image Result

    Effects of α-LA and ovalbumin (OVA) on mucin synthesis in RGM1 cells. Values represent mean±SEM for 5 cultures. *P<0.05, compared with the control.

    Effects of α-LA and ovalbumin (OVA) on mucin synthesis in RGM1 cells. Values represent mean±SEM for 5 cultures. *P<0.05, compared with the control.

  • Image Result

    Effects of α-LA and ovalbumin (OVA) on mucin secretion in RGM1 cells. Values represent mean±SEM for 5 cultures. **P<0.01, compared with the control.

    Effects of α-LA and ovalbumin (OVA) on mucin secretion in RGM1 cells. Values represent mean±SEM for 5 cultures. **P<0.01, compared with the control.

  • Image Result

    Effects of α-LA and ovalbumin (OVA) on prostaglandin E2 synthesis in RGM1 cells. Values represent mean±SEM for 5 cultures. ***P<0.001, compared with the control.

    Effects of α-LA and ovalbumin (OVA) on prostaglandin E2 synthesis in RGM1 cells. Values represent mean±SEM for 5 cultures. ***P<0.001, compared with the control.

  • Image Result

    Effects of α-LA on periodic acid-Schiff (PAS)-positive mucus in the gastric mucosa in rats. (A) Representative photomicrographs of corpus and antrum mucosa from control and α-LA-treated rats. Sections

    Effects of α-LA on periodic acid-Schiff (PAS)-positive mucus in the gastric mucosa in rats. (A) Representative photomicrographs of corpus and antrum mucosa from control and α-LA-treated rats. Sections were stained using PAS reagent. Original magnification: 33×. (B) Thickness ratio of the mucus gel layer to the lamina propria mucosae in corpus and antrum mucosa. Values represent mean±SEM for 6 rats. *P<0.05, compared with the control.

PII: S0022-0302(07)71537-0

doi: 10.3168/jds.S0022-0302(07)71537-0

Journal of Dairy Science
Volume 90, Issue 2 , Pages 541-546 , February 2007