Journal of Dairy Science
Volume 91, Issue 9 , Pages 3337-3342 , September 2008

Concentrations of Ganglioside Type M1 and Immunoglobulin G in Colostrum Are Inversely Related to Bacterial Infection at Early Lactation in Cows

  • G. Leitner

      Affiliations

    • National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    • Corresponding Author InformationCorresponding author.
    • ,
  • O. Krifucks

      Affiliations

    • National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    • ,
  • S. Jacoby

      Affiliations

    • Institute of Animal Science, The Volcani Center, PO Box 6, Bet Dagan 50250, Israel
    • ,
  • Y. Lavi

      Affiliations

    • PO Box 322, Sha’ar Efraim 42835, Israel
    • ,
  • N. Silanikove

      Affiliations

    • Biology of Lactation Laboratory, A.R.O., The Volcani Center, PO Box 6, Bet Dagan 50250, Israel

Received 10 January 2008 ,Accepted 23 May 2008.

References 

  1. Bode L, Beermann C, Mank M, Kohn G, Boehm G. Human and bovine milk gangliosides differ in their fatty acid composition. J. Nutr. 2004;134:3016–3020
  2. Colarow L, Turini M, Tenenberg S, Berger A. Characterization and biological activity of gangliosides in buffalo milk. Biochim. Biophys. Acta. 2003;1631:94–106
  3. Cross ML, Gill SH. Immunomodulatory properties of milk. Br. J. Nutr. 2000;84:81–89
  4. de Bentzmann S, Roger P, Dupuit F, Bajolet-Laudinat O, Fuchey C, Plotkowski MC, et al. Asialo GM1 is a receptor for Pseudomonas aeruginosa adherence to regenerating respiratory epithelial cells. Infect. Immun. 1996;64:1582–1588
  5. Feldman M, Bryan R, Rajan S, Scheffler L, Brunnert S, Tang H, et al. Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection. Infect. Immun. 1998;66:43–51
  6. Fox LK, Chester ST, Hallberg JW, Nickerson SC, Pankey JW, Weaver LD. Survey of intramammary infections in dairy heifers at breeding age and first parturition. J. Dairy Sci. 1995;78:1619–1628
  7. Goff JP. Major advances in our understanding of nutritional influences on bovine health. J. Dairy Sci. 2006;89:1292–1301
  8. Hakomori S. Structure and function of sphingoglycolipids in transmembrane signaling and cell-cell interactions. Biochem. Soc. Trans. 1993;21:583–595
  9. Jaster EH. Evaluation of quality, quantity, and timing of colostrum feeding on immunoglobulin G1 absorption in Jersey calves. J. Dairy Sci. 2005;88:296–302
  10. Keenan TW. Composition and synthesis of gangliosides in mammary gland and milk of the bovine. Biochim. Biophys. Acta. 1974;337:255–270
  11. Keenan TW, Morre DJ, Huang CM. Distribution of gangliosides among fractions from rat liver and bovine mammary gland. FEBS Lett. 1972;24:204–208
  12. Laegreid A, Otnaess AB. Trace amounts of ganglioside GM1 in human milk inhibit enterotoxins from Vibrio cholerae and Escherichia coli. Life Sci. 1987;40:55–62
  13. Laegreid A, Otnaess AB, Fuglesang J. Human and bovine milk: Comparison of ganglioside composition and enterotoxin-inhibitory activity. Pediatr. Res. 1986;20:416–421
  14. Lanne B, Uggla L, Stenhagen G, Karlsson KA. Enhanced binding of enterotoxigenic Escherichia coli K99 to amide derivates of the receptor ganglioside NeuGs-GM3. Biochemistry. 1995;34:1845–1850
  15. Lee KK, Yu L, Macdonald LD, Paranchych W, Hoges SR, Irvin TR. Anti-adhesin antibodies that recognize a receptor-binding motif (adhesintope) inhibit pilus/fimbrial-mediated adherence of Pseudomonas aeruginosa and Candida albicans to asialo-GM1 receptors and human buccal epithelial cell surface receptors. Can. J. Microbiol. 1996;42:479–486
  16. Leitner G, Merin U, Lavi Y, Egber A, Silanikove N. Atiology of intramammary infection and its effect on milk composition in goat flocks. J. Dairy Res. 2007;74:186–193
  17. Leitner G, Yadlin B, Glickman A, Chaffer M, Saran A. Systemic and local immune response of cows to intramammary infection with Staphyloccus aureus. Res. Vet. Sci. 2000;69:181–184
  18. Martin M-J, Martin-Sosa S, Garcia LA, Hueso P. Distribution of bovine milk sialoglycoconjugates during lactation. J. Dairy Sci. 2001;84:995–1000
  19. Miller RH, Guidry AJ, Paape MJ, Dulin AM, Fulton LA. Relationship between immunoglobulin concentrations in milk and phagocytosis by bovine neutrophils. Am. J. Vet. Res. 1988;49:42–45
  20. Minke WE, Roach C, Hol WG, Verlinde CL. Structure-based exploration of the ganglioside GM1 binding sites of Escherichia coli heat-labile enterotoxin and cholera toxin for the discovery of receptor antagonists. Biochemistry. 1999;38:5684–5692
  21. Morin DE, McCoy GC, Hurley WL. Effects of quality, quantity, and timing of colostrum feeding and addition of a dried colostrum supplement on immunoglobulin G1 absorption in Holstein bull calves. J. Dairy Sci. 1997;80:747–753
  22. Nakamura T, Kawase H, Kimara K, Watanabe Y, Ohtani M. Concentrations of sialyloligosaccharides in bovine colostrum and milk during prepartum and early lactation. J. Dairy Sci. 2003;86:1315–1320
  23. Nickerson SC. Immunological aspects of mammary involution. J. Dairy Sci. 1989;72:1665–1678
  24. Nickerson SC, Owens WE, Boddie RL. Mastitis indairy heifers: Initial studies on prevalence and control. J. Dairy Sci. 1995;78:1607–1618
  25. Noda M, Kato I, Hirayama T, Matsuda F. Fixation and inactivation of staphylococcal leucocidin by phosphatidylcholine and ganglioside GM1 in rabbit polymorphonuclear leukocytes. Infect. Immun. 1980;29:678–684
  26. Oliver PS, Gonzalez RN, Hogan JS, Jayarao BM, Owens WE. Microbiological Procedures for the Diagnosis of Bovine Udder Infection and Determination of Milk Quality. 4th ed. Verona, WI: National Mastitis Council Inc; 2004;
  27. Oliver SP, Sordillo LM. Approaches to the manipulationof mammary involution. J. Dairy Sci. 1989;72:1647–1664
  28. Ozawa T, Kaneko J, Narya H, Izaki K, Kamio Y. Inactivation of gamma-hemolisin H gamma II component by addition of monosialoganglioside GM1 to human erythrocytes. Biosci. Biotechnol. Biochem. 1994;58:602–605
  29. Pan XL, Izumi T. Variation of the ganglioside compositions of human milk, cow's milk and infant formulas. Early Hum. Dev. 2000;57:25–31
  30. Piccinini R, Binda E, Belotti M, Daprà V, Zecconi A. Evaluation of milk components during whole lactation in healthy quarters. J. Dairy Res. 2007;74:226–232
  31. Puente R, Garcia-Pardo L-A, Hueso P. Gangliosides in bovine milk. Changes in content and distribution of individual ganglioside levels during lactation. Biol. Chem. Hoppe Seyler. 1992;373:283–288
  32. Quigley JD, Drewry JJ. Nutrient and immunity transfer from cow to calf pre-and postcalving. J. Dairy Sci. 1998;81:2779–2790
  33. SAS Institute. JMP Statistics and Graphics Guide, Version 5. Cary, NC: SAS Institute Inc; 2002;
  34. Shamay A, Homans R, Fuerman Y, Levin I, Barash H, Silanikove N, et al. Expression of albumin in nonhepatic tissues and its synthesis by the bovine mammary gland. J. Dairy Sci. 2005;88:569–576
  35. Shamay A, Shapiro F, Leitner G, Silanikove N. Infusions of casein hydrolyzates into the mammary gland disrupt tight junction integrity and induce involution in cows. J. Dairy Sci. 2003;86:1250–1258
  36. Silanikove N, Shapiro F, Leitner G. Postranscriptional regulation of xanthine oxidase activity in bovine milk by its substrates: Interaction with the bacteria commonly involved in subclinical infection of the mammary gland. Biochem. Biophys. Res. Commun. 2007;363:561–565
  37. Sordillo LM. Factors affecting mammary gland immunity and mastitis susceptibility. Livest. Prod. Sci. 2005;98:89–99
  38. Sordillo LM, O’Boyle N, Gandy JC, Corl CM, Hamilton E. Shifts in thioredoxin reductase activity and oxidant status in mononuclear cells obtained from transition dairy cattle. J. Dairy Sci. 2007;90:1186–1192
  39. Takamiya K, Yamamoto A, Furukawa K, Zhao J, Fukumoto S, Yamashiro S, et al. Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone. Proc. Natl. Acad. Sci. USA. 1998;95:12147–12152
  40. Watson ED. Specific antibody in milk whey and phagocytosis of Actinomyces pyogenes by neutrophils in vitro. Res. Vet. Sci. 1989;47:253–256
  41. Yamaguchi S, Miyazaki Y, Oka S, Yano I. Stimulatory effect of gangliosides on phagocytosis, phagosome-lysosome fusion, and intracellular signal transduction system by human polymorphonuclear leukocytes. Glycoconj. J. 1997;14:707–714
  42. Younis A, Leitner G, Heller ED, Samra Z, Gadba R, Lubashevsky G, et al. Phenotypic characteristics of Staphylococcus aureus isolated from bovine mastitis in Israeli dairy herds. J. Vet. Med. B. 2000;47:591–598

PII: S0022-0302(08)71048-8

doi: 10.3168/jds.2008-1010

Journal of Dairy Science
Volume 91, Issue 9 , Pages 3337-3342 , September 2008

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