Journal of Dairy Science
Volume 91, Issue 7 , Pages 2591-2594 , July 2008

Short Communication: Immunity Gene pedB Enhances Production of Pediocin PA-1 in Naturally Resistant Lactococcus lactis Strains

  • J.L. Arqués

      Affiliations

    • Commensals and Microflora, BBSRC Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    • Corresponding Author InformationCorresponding author.
    • ,
  • J.M. Rodríguez

      Affiliations

    • Departamento de Nutrición y Bromatología III, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
    • ,
  • M.J. Gasson

      Affiliations

    • Commensals and Microflora, BBSRC Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom
    • ,
  • N. Horn

      Affiliations

    • Commensals and Microflora, BBSRC Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, United Kingdom

Received 8 October 2007 ,Accepted 5 March 2008.

References 

  1. Dodd HM, Horn N, Chan WC, Giffard CJ, Bycroft BW, Roberts GCK, et al. Molecular analysis of the regulation of nisin immunity. Microbiology. 1996;142:2385–2392
  2. Dodd HM, Horn N, Gasson MJ. Analysis of the genetic determinant for production of the peptide antibiotic nisin. J. Gen. Microbiol. 1990;136:555–566
  3. Dodd HM, Horn N, Zhang H, Gasson MJ. A lactococcal expression system for engineered nisins. Appl. Environ. Microbiol. 1992;58:3683–3693
  4. Eijsink VGH, Skeie M, Middelhoven H, Brurberg MB, Nes IF. Comparative studies of pediocin-like bacteriocins. Appl. Environ. Microbiol. 1998;64:3275–3281
  5. Fimland G, Eijsink VGH, Nissen-Meyer J. Comparative studies of immunity proteins of pediocin-like bacteriocins. Microbiology. 2002;148:3661–3670
  6. Gasson MJ, Anderson PH. High copy number plasmid vectors for use in lactic streptococci. FEMS Microbiol. Lett. 1985;30:193–196
  7. Hanlin MB, Kalchayanand N, Ray P, Ray B. Bacteriocins of lactic acid bacteria in combination have greater antibacterial activity. J. Food Prot. 1993;56:252–255
  8. Havarstein LS, Diep DB, Nes IF. A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export. Mol. Microbiol. 1995;16:229–240
  9. Holo H, Nilssen O, Nes IF. Lactococcin A, a new bacteriocin from Lactococcus lactis subsp. cremoris: Isolation and characterization of the protein and its gene. J. Bacteriol. 1991;173:3879–3887
  10. Horn N, Fernández A, Dodd HM, Gasson MJ, Rodríguez JM. Nisin-controlled production of pediocin PA-1 and colicin V in nisin- and non-nisin-producing Lactococcus lactis strains. Appl. Environ. Microbiol. 2004;70:5030–5032
  11. Horn N, Martínez MI, Martínez JM, Hernández PE, Gasson MJ, Rodríguez JM, et al. Production of pediocin PA-1 by Lactococcus lactis using the lactococcin A secretory apparatus. Appl. Environ. Microbiol. 1998;64:818–823
  12. Horn N, Martínez MI, Martínez JM, Hernández PE, Gasson MJ, Rodríguez JM, et al. Enhanced production of pediocin PA-1 and coproduction of nisin and pediocin PA-1 by Lactococcus lactis. Appl. Environ. Microbiol. 1999;65:4443–4450
  13. Joosten HMLJ, Rodríguez E, Núñez M. PCR detection of sequences similar to the AS-48 structural gene in bacteriocin-producing enterococci. Lett. Appl. Microbiol. 1997;24:40–42
  14. Kemperman R, Jonker M, Nauta A, Kuipers OP, Kok J. Functional analysis of the gene cluster involved in production of the bacteriocin circularin A by Clostridium beijerinckii ATCC 25752. Appl. Environ. Microbiol. 2003;69:5839–5848
  15. Martínez JM, Martínez MI, Suárez AM, Herranz C, Casaus P, Cintas LJ, et al. Antibodies to a synthetic 1–9-N-terminal amino acid fragment of mature pediocin PA-1: Sensitivity and specificity for pediocin PA-1 and cross-reactivity against Class IIa bacteriocins. Microbiology. 1999;145:2777–2787
  16. Matsumoto-Nakano M, Kuramitsu HK. Role of bacteriocin immunity proteins in the antimicrobial sensitivity of Streptococcus mutans. J. Bacteriol. 2006;188:8095–8102
  17. Mulet-Powell N, Lacoste-Armynot AM, Viñas M, de Buochberg MS. Interactions between pairs of bacteriocins from lactic acid bacteria. J. Food Prot. 1998;61:1210–1212
  18. Quadri LEN, Kleerebezem M, Kuipers OP, de Vos WM, Roy KL, Vederas JC, et al. Characterization of a locus from Carnobacterium piscicola LV17B involved in bacteriocin production and immunity: Evidence for global inducer-mediated transcription regulation. J. Bacteriol. 1997;179:6163–6171
  19. Reviriego C, Fernández A, Horn N, Rodríguez E, Marín ML, Fernández L, et al. Production of pediocin PA-1, and coproduction of nisin A and pediocin PA-1, by wild Lactococcus lactis strains of dairy origin. Int. Dairy J. 2005;15:45–49
  20. Reviriego C, Fernández L, Kuipers OP, Kok J, Rodriguez JM. Enhanced production of pediocin PA-1 in wild nisin- and non-nisin-producing Lactococcus lactis strains of dairy origin. Int. Dairy J. 2007;17:574–577
  21. Rodríguez E, Calzada J, Arqués JL, Rodríguez JM, Nuñez M, Medina M. Antimicrobial activity of pediocin-producing Lactococcus lactis on Listeria monocytogenes, Staphylococcus aureus and Escherichia coli O157:H7 in cheese. Int. Dairy J. 2005;15:51–57
  22. Rodríguez JM, Cintas LM, Casaus P, Martínez MI, Suárez A, Hernández PE. Detection of pediocin PA-1-producing pediococci by rapid molecular biology techniques. Food Microbiol. 1997;14:363–371
  23. Rodríguez JM, Martínez MI, Kok J. Pediocin PA-1, a wide-spectrum bacteriocin from lactic acid bacteria. Crit. Rev. Food Sci. Tech. 2002;42:91–121
  24. Simon D, Chopin A. Construction of a vector plasmid family and its use for molecular cloning in Streptococcus lactis. Biochimie. 1988;70:559–566
  25. Stein T, Heinzmann S, Solovieva I, Etian KD. Function of Lactococcus lactis nisin immunity genes nisI and nisFEG after coordinated expression in the surrogate host Bacillus subtilis. J. Biol. Chem. 2003;278:89–94
  26. Van Belkum MJ, Worobo RW, Stiles ME. Double-glycine-type leader peptides direct secretion of bacteriocins by ABC transporters: Colicin V secretion in Lactococcus lactis. Mol. Microbiol. 1997;23:1293–1301

PII: S0022-0302(08)71133-0

doi: 10.3168/jds.2007-0759

Journal of Dairy Science
Volume 91, Issue 7 , Pages 2591-2594 , July 2008

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