Journal of Dairy Science
Volume 92, Issue 7 , Pages 3019-3026 , July 2009

Prevalence of bacteriophages infecting Staphylococcus aureus in dairy samples and their potential as biocontrol agents

  • P. García

      Affiliations

    • Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Apdo. 85, 33300 Villaviciosa, Asturias, Spain
    • Corresponding Author InformationCorresponding author.
    • ,
  • C. Madera

      Affiliations

    • Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Apdo. 85, 33300 Villaviciosa, Asturias, Spain
    • ,
  • B. Martínez

      Affiliations

    • Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Apdo. 85, 33300 Villaviciosa, Asturias, Spain
    • ,
  • A. Rodríguez

      Affiliations

    • Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Apdo. 85, 33300 Villaviciosa, Asturias, Spain
    • ,
  • J. Evaristo Suárez

      Affiliations

    • Área de Microbiología, Facultad de Medicina, Universidad de Oviedo, Spain

Received 24 September 2008 ,Accepted 3 March 2009.

References 

  1. Cairns BJ, Timms AR, Jansen VAA, Connerton IF, Payne RJH. Quantitative models of in vitro bacteriophage-host dynamics and their application to phage therapy. PLoS Pathog. 2009;5:e1000253
  2. Carlton RM, Noordman WH, Biswas B, de Meester ED, Loessner MJ. Bacteriophage P100 for control of Listeria monocytogenes in foods: Genome sequence, bioinformatic analyses, oral toxicity study, and application. Regul. Toxicol. Pharmacol. 2005;43:301–312
  3. Civerolo EL. Bacteriophages. In:  Klement Z,  Rudolph K,  Sands DC editor. Methods in Phytobacteriology. Budapest, Hungary: Akademiai Kiado; 1990;p. 205–213
  4. Dinges MM, Orwin PM, Schlievert PM. Exotoxins of Staphylococcus aureus. Clin. Microbiol. Rev. 2000;13:16–64
  5. FDA. Food additives permitted for direct addition to food for human consumption; bacteriophage preparation. Fed. Regist. 2006;71:47729–47732
  6. García P, Madera C, Martínez B, Rodríguez A. Biocontrol of Staphylococcus aureus in curd manufacturing processes using bacteriophages. Int. Dairy J. 2007;17:1232–1239
  7. Gill JJ, Sabour PM, Leslie KE, Griffiths MW. Bovine whey proteins inhibit the interaction of Staphylococcus aureus and bacteriophage K. J. Appl. Microbiol. 2006;101:377–386
  8. Gruet P, Maicent P, Berthelot X, Kaltsatos V. Bovine mastitis and intramammary drug delivery: review and perspectives. Adv. Drug Deliv. Rev. 2001;50:245–259
  9. Hagens S, Loessner MJ. Application of bacteriophages for detection and control of foodborne pathogens. Appl. Microbiol. Biotechnol. 2007;76:513–519
  10. Hanlon GW. Bacteriophages: An appraisal of their role in the treatment of bacterial infections. Int. J. Antimicrob. Agents. 2007;30:118–128
  11. Hudson JA, Billington C, Carey-Smith C, Greening G. Bacteriophages as biocontrol agents in food. J. Food Prot. 2005;68:426–437
  12. Ikeda T, Tamate N, Yamaguchi K, Makino S. Quantitative analysis of Staphylococcus aureus in skimmed milk powder by real-time PCR. J. Vet. Med. Sci. 2005;67:1037–1041
  13. Kasman LM, Kasman A, Westwater C, Dolan J, Schmidt MG, Norris JS. Overcoming the phage replication threshold: A mathematical model with implications for phage therapy. J. Virol. 2002;76:5557–5564
  14. Kutter E, Sulakvelidze A. Bacteriophages Biology and Applications. Boca Raton, FL: CRC Press; 2005;
  15. Kwan T, Liu J, Dubow M, Gros P, Pelletier J. The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proc. Natl. Acad. Sci. USA. 2005;102:5174–5179
  16. Ladero V, García P, Bascarán V, Herrero M, Álvarez MA, Suárez JE. Identification of the repressor-encoding gene of the temperate bacteriophage A2. J. Bacteriol. 1998;180:3474–3476
  17. Le Loir Y, Baron F, Gautier M. Staphylococcus aureus and food poisoning. Genet. Mol. Res. 2003;2:63–76
  18. Madera C, Monjardín C, Suárez JE. Milk contamination and resistance to processing conditions determine the fate of Lactococcus lactis bacteriophages in dairies. Appl. Environ. Microbiol. 2004;70:7365–7371
  19. Makovec JA, Ruegg PL. Antimicrobial resistance of bacteria isolated from dairy cow milk samples submitted for bacterial culture: 8,905 samples (1994–2001). J. Am. Vet. Med. Assoc. 2003;222:1582–1589
  20. Mann NH. The potential of phages to prevent MRSA infections. Res. Microbiol. 2008;159:400–405
  21. Matsuzaki S, Rashel M, Uchiyama J, Sakurai S, Ujihara T, Kuroda M, et al. Bacteriophage therapy: A revitalized therapy against bacterial infectious diseases. J. Infect. Chemother. 2005;1:211–219
  22. Modi R, Hirvi Y, Hill A, Griffiths MW. Effect of phage on survival of Salmonella Enteritidis during manufacture and storage of Cheddar cheese made from raw and pasteurized milk. J. Food Prot. 2001;64:927–933
  23. O’Flaherty S, Coffey A, Meaney WJ, Fitzgerald GF, Ross RP. Inhibition of bacteriophage K proliferation on Staphylococcus aureus in raw bovine milk. Lett. Appl. Microbiol. 2005;41:274–279
  24. O’Flaherty S, Ross RP, Flynn J, Meaney WJ, Fitzgerald GF, Coffey A. Isolation and characterization of two anti-staphylococcal bacteriophages specific for pathogenic Staphylococcus aureus associated with bovine infections. Lett. Appl. Microbiol. 2005;41:482–486
  25. Priest F, Austin B. Numerical taxonomy. In:  Priest F,  Austin B editor. Modern Bacterial Taxonomy. London, UK: Chapman and Hall; 1995;p. 14–49
  26. Sambrook J, Maniatis T, Fritsch EF. Molecular Cloning: A Laboratory Manual. 2nd ed.. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1989;
  27. Skurnik M, Strauch E. Phage therapy: Facts and fiction. Int. J. Med. Microbiol. 2006;296:5–14
  28. WHO (World Health Organization). 2000. Surveillance Report: Programme for Control of Foodborne Infections and Intoxications in Europe. 8th Report 1999–2000. http://www.bfr.bund.de/internet/8threport/8threp_fr.htm.
  29. Waldvogel FA. Staphylococcus aureus (including staphylococcal toxic shock). In:  Mandell JL,  Bennett JE,  Dolin R editor. Principles and Practice of Infectious Diseases. Philadelphia, PA: Churchill Livingstone; 2001;p. 2069–2092

PII: S0022-0302(09)70618-6

doi: 10.3168/jds.2008-1744

Journal of Dairy Science
Volume 92, Issue 7 , Pages 3019-3026 , July 2009

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