Effects of prepartum 2,4-thiazolidinedione on metabolism and performance in transition dairy cows

Postpartum BCS of cows administered increasing amounts of thiazolidinedione (TZD) during the prepartum period. Values are least squares means, with error bars representing the SEM; n = 12 for saline, n = 12 for 2.0mg of TZD/kg of BW, and n = 12 for 4.0mg of TZD/kg of BW. The P-value for the overall linear effect of TZD was <0.001, the P-value for the overall quadratic effect of TZD was 0.88, and the P-value for the interaction of treatment and week was 0.03.