Journal of Dairy Science
Volume 92, Issue 8 , Pages 3623-3633 , August 2009

Effects of prepartum 2,4-thiazolidinedione on metabolism and performance in transition dairy cows

Received 1 July 2008 ,Accepted 31 March 2009.

References 

  1. Allen MS, Bradford BJ, Harvatine KJ. The cow as a model to study food intake regulation. Annu. Rev. Nutr. 2005;25:523–547
  2. Bajaj M, Suraamornkul S, Pratipanawatr T, Hardies LJ, Pratipanawatr W, Glass L, et al. Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes. Diabetes. 2003;52:1364–1370
  3. Bauman DE, Currie WB. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci. 1980;63:1514–1529
  4. Bauman DE, Elliot JM. Control of nutrient partitioning in lactating ruminants. In:  Mepham TB editors. Biochemistry of Lactation. Amsterdam, the Netherlands: Elsevier Science Publishers; 1983;p. 437–468
  5. Beam SW, Butler WR. Energy balance and ovarian follicle development prior to the first ovulation postpartum in dairy cows receiving three levels of dietary fat. Biol. Reprod. 1997;56:133–142
  6. Bell AW. Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. J. Anim. Sci. 1995;73:2804–2819
  7. Bobe G, Young JW, Beitz DC. Invited review: Pathology, etiology, prevention, and treatment of fatty liver in dairy cows. J. Dairy Sci. 2004;87:3105–3124
  8. Butler WR. Nutritional interactions with reproductive performance in dairy cattle. Anim. Reprod. Sci. 2000;60-61:449–457
  9. Davis CL, Drackley JK. The Development, Nutrition, and Management of the Young Calf. Ames: Iowa State University Press; 1998;
  10. Drackley JK, Overton TR, Douglas GN. Adaptations of glucose and long-chain fatty acid metabolism in liver of dairy cows during the periparturient period. J. Dairy Sci. 2001;84(E Suppl):E100–E112
  11. Drackley JK, Richard MJ, Beitz DC, Young JW. Metabolic changes in dairy cows with ketonemia in response to feed restriction and dietary 1,3-butanediol. J. Dairy Sci. 1992;75:1622–1634
  12. Ehrhardt RA, Slepetis RM, Bell AW, Boisclair YR. Maternal leptin is elevated during pregnancy in sheep. Domest. Anim. Endocrinol. 2001;21:85–96
  13. Guo L, Tabrizchi R. Peroxisome proliferator-activated receptor gamma as a drug target in the pathogenesis of insulin resistance. Pharmacol. Ther. 2006;111:145–173
  14. Hammarstedt A, Andersson CX, Rotter Sopasakis V, Smith U. The effect of PPAR-γ ligands on the adipose tissue in insulin resistance. Prostaglandins Leukot. Essent. Fatty Acids. 2005;73:65–75
  15. Harvatine KJ, Bauman DE. Expression of PPAR and LXR nuclear hormone receptor families are not modified during milk fat depression induced by diet or treatment with trans-10, cis-12 conjugated linoleic acid (CLA). J. Dairy Sci. 2007;90(Suppl. 1):59;(Abstr.)
  16. Houseknecht KL, Cole BM, Steele PJ. Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: A review. Domest. Anim. Endocrinol. 2002;22:1–23
  17. Joosen AMCP, Bakker AHF, Gering MJA, Westerterp KR. The effect of PPARγ ligand rosiglitazone on energy balance regulation. Diabetes Metab. Res. Rev. 2006;22:204–210
  18. Jorritsma R, Wensing T, Kruip TAM, Vos PLAM, Noordhuizen PTM. Metabolic changes in early lactation and impaired reproductive performance in dairy cows. Vet. Res. 2003;34:11–26
  19. Klinkner DB, Lim HJ, Strawn EY, Oldham KT, Sander TL. An in vivo murine model of rosiglitazone use in pregnancy. Fertil. Steril. 2006;86:1074–1079
  20. Kushibiki S, Hodate K, Shingu H, Obara Y, Touno E, Shinoda M, et al. Metabolic and lactational responses during recombinant bovine tumor necrosis factor-α treatment in lactating cows. J. Dairy Sci. 2003;86:819–827
  21. Kushibiki S, Hodate K, Shingu H, Ueda Y, Shinoda M, Mori Y, et al. Insulin resistance induced in dairy steers by tumor necrosis factor alpha is partially reversed by 2,4-thiazolidinedione. Domest. Anim. Endocrinol. 2001;21:25–37
  22. Larsen PJ, Jensen PB, Sørensen RV, Larsen LK, Vrang N, Wulff EM, et al. Differential influences of peroxisome proliferator-activated receptors-γ and -α on food intake and energy homeostasis. Diabetes. 2003;52:2249–2259
  23. Loor JJ, Dann HM, Everts RE, Oliveira R, Green CA, Janovick Guretzky NA, et al. Temporal gene expression profiling of liver from periparturient dairy cows reveals complex adaptive mechanisms in hepatic function. Physiol. Genomics. 2005;23:217–226
  24. Lucy MC, Staples CR, Michel FM, Thatcher WW. Energy balance and size and number of ovarian follicles detected by ultrasonography in early postpartum dairy cows. J. Dairy Sci. 1991;74:473–482
  25. Mayerson AB, Hundal RS, Dufour S, Lebon V, Befroy D, Cline GW, et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes. 2002;51:797–802
  26. McNamara JP. Regulation of adipose tissue metabolism in support of lactation. J. Dairy Sci. 1991;74:706–719
  27. Nara BS, First NL. Effect of indomethacin and prostaglandin F2α on parturition in swine. J. Anim. Sci. 1981;52:1360–1370
  28. NRC. Nutrient Requirements of Dairy Cattle. 7th rev. ed.. Washington, DC: Natl. Acad. Press; 2001;
  29. Overton TR, Waldron MR. Nutritional management of transition dairy cows: Strategies to optimize metabolic health. J. Dairy Sci. 2004;87(E Suppl.):E105–E119
  30. Petterson JA, Dunshea FR, Ehrhardt RA, Bell AW. Pregnancy and undernutrition alter glucose metabolic responses to insulin in sheep. J. Nutr. 1993;123:1286–1295
  31. Petterson JA, Slepetis R, Ehrhardt RA, Dunshea FR, Bell AW. Pregnancy but not moderate undernutrition attenuates insulin suppression of fat mobilization in sheep. J. Nutr. 1994;124:2431–2436
  32. Pires JAA, Souza AH, Grummer RR. Induction of hyperlipidemia by intravenous infusion of tallow emulsion causes insulin resistance in Holstein cows. J. Dairy Sci. 2007;90:2735–2744
  33. Reynolds CK, Aikman PC, Lupoli B, Humphries DJ, Beever DE. Splanchnic metabolism of dairy cows during the transition from late gestation through early lactation. J. Dairy Sci. 2003;86:1201–1217
  34. Roche JF. The effect of nutritional management of the dairy cow on reproductive efficiency. Anim. Reprod. Sci. 2006;96:282–296
  35. Saitoh Y, Liu R, Ueno H, Mizuta M, Nakazato M. Oral pioglitazone administration increases food intake through ghrelin-independent pathway in Zucker fatty rat. Diabetes Res. Clin. Pract. 2007;77:351–356
  36. SAS Institute. SAS User's Guide: Statistics, Version 8 Edition. Cary, NC: SAS Inst. Inc.; 2001;
  37. Schroeder, J. W. 1997. Mastitis control programs: Bovine mastitis and milking management. Fact sheet AS-1129, North Dakota State University. http://www.ag.ndsu.edu/pubs/ansci/dairy/as1129w.htm Accessed Oct. 21, 2008.
  38. Sevillano J, Lopez-Perez IC, Herrera E, Del Pilar Ramos M, Bocos C. Englitazone administration to late pregnant rats produces delayed body growth and insulin resistance in their fetuses and neonates. Biochem. J. 2005;389:913–918
  39. Sharma AM, Staels B. Peroxisome proliferator-activated receptor γ and adipose tissue—Understanding obesity-related changes in regulation of lipid and glucose metabolism. J. Clin. Endocrinol. Metab. 2007;92:386–395
  40. Shimizu H, Tsuchiya T, Sato N, Shimomura Y, Kobayashi I, Mori M. Troglitazone reduces plasma leptin concentration but increases hunger in NIDDM patients. Diabetes Care. 1998;21:1470–1474
  41. Smith, K. L. 2004. Effects of prepartum carbohydrate source and chromium supplementation in dairy cows during the periparturient period. MS Thesis. Cornell Univ., Ithaca, NY.
  42. Smith KL, Stebulis SE, Waldron MR, Overton TR. Prepartum 2,4-thiazolidinedione alters metabolic dynamics and dry matter intake of dairy cows. J. Dairy Sci. 2007;90:3660–3670
  43. Staigmiller RB, Short RE, Bellows RA, Carr JB. Effect of nutrition on response to exogenous FSH in beef cattle. J. Anim. Sci. 1979;48:1182–1190
  44. Sundvold H, Brzozowska A, Lien S. Characterisation of bovine peroxisome proliferator-activated receptors gamma 1 and gamma 2: Genetic mapping and differential expression of the two isoforms. Biochem. Biophys. Res. Commun. 1997;239:857–861
  45. Tordjman J, Chauvet G, Quette J, Beale EG, Forest C, Antoine B. Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells. J. Biol. Chem. 2003;278:18785–18790
  46. Vernon RG. Lipid metabolism during lactation: A review of adipose tissue-liver interactions and the development of fatty liver. J. Dairy Res. 2005;72:460–469
  47. Wildman EE, Jones GM, Wagner PE, Bowman RL, Trout HF, Lesch TN. A dairy cow body condition scoring system and its relationship to selected production variables in high producing Holstein dairy cattle. J. Dairy Sci. 1982;65:495–501
  48. Wolden-Hanson T, Marck BT, Matsumoto AM. Troglitazone treatment of aging Brown Norway rats improves food intake and weight gain after fasting without increasing hypothalamic NPY gene expression. Exp. Gerontol. 2002;37:679–691

PII: S0022-0302(09)70683-6

doi: 10.3168/jds.2008-1508

Journal of Dairy Science
Volume 92, Issue 8 , Pages 3623-3633 , August 2009

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