Journal of Dairy Science
Volume 93, Issue 6 , Pages 2703-2717 , June 2010

Testing candidate gene effects on milk production traits in dairy cattle under various parameterizations and modes of inheritance

  • T. Suchocki

      Affiliations

    • Department of Animal Genetics, Wrocław University of Environmental and Life Sciences, Kożuchowska 7, 51-631 Wrocław, Poland
    • ,
  • J. Komisarek

      Affiliations

    • Department of Cattle Breeding and Milk Production, Poznan University of Life Sciences, Wojska Polskiego 71 A, 60-625 Poznań, Poland
    • ,
  • J. Szyda

      Affiliations

    • Department of Animal Genetics, Wrocław University of Environmental and Life Sciences, Kożuchowska 7, 51-631 Wrocław, Poland
    • Institute of Natural Sciences, Wrocław University of Life Sciences, Norwida 25, 50-375 Wrocław, Poland
    • Corresponding Author InformationCorresponding author.

Received 6 July 2009 ,Accepted 10 February 2010.

References 

  1. Álvarez-Castro JM, Carlborg Ö. A unified model for functional and statistical epistasis and its application in quantitative trait loci analysis. Genetics. 2007;176:1151–1167
  2. Bennewitz J, Reinsch N, Paul S, Looft C, Kaupe B, Weimann C, et al. The DGAT1 K232A mutation is not solely responsible for the milk production quantitative trait locus on the bovine chromosome 14. J. Dairy Sci. 2004;87:431–442
  3. Chen HC, Smith JS, Ladha Z, Jensen DR, Ferreira LD, Pulawa LK, et al. Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1. J. Clin. Invest. 2002;109:1049–1055
  4. Chen HC, Smith JS, Tow B, Elias PM, Farese RV. Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands. J. Clin. Invest. 2002;109:175–181
  5. Cockerham CC. An extension of the concept of partitioning hereditary variance for analysis of covariances among relatives when epistasis is present. Genetics. 1954;39:859–882
  6. Feuermann Y, Mabjeesh SJ, Shamay A. Leptin affects prolactin action on milk protein and fat synthesis in the bovine mammary gland. J. Dairy Sci. 2004;87:2941–2946
  7. Gautier M, Capitan A, Fritz A, Eggen A, Boichard D, Druet T. Characterization of the DGAT1 K232A and variable number of tandem repeat polymorphisms in French dairy cattle. J. Dairy Sci. 2007;90:2980–2988
  8. Goddard ME, Hayes BJ. Genomic selection. J. Anim. Breed. Genet. 2007;124:323–330
  9. Grisart B, Coppieters Q, Farnir F, Karim L, Ford C, Berzi P, et al. Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition. Genome Res. 2002;12:222–231
  10. Grisart B, Farnir F, Karim L, Cambisano N, Kim J-J, Kvasz A, et al. Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition. Proc. Natl. Acad. Sci. USA. 2004;101:2398–2403
  11. Henderson CR. Applications of Linear Models in Animal Breeding. Ontario, Canada.: University of Guelph; 1984;
  12. Ibeagha-Awemu EM, Kgwatalala P, Zhao X. A critical analysis of production-associated DNA polymorphisms in the genes of cattle, goat, sheep, and pig. Mamm. Genome. 2008;19:226–245
  13. Jiang JJ, Conrath DW. Semantic similarity based on corpus statistics and lexical taxonomy. In: Proceedings of International Conference Research on Computational Linguistics (ROCLING X). Taiwan. 1997;
  14. Kao CH, Zeng ZB. Modelling epistasis of quantitative trait loci using Cockerham's model. Genetics. 2002;160:1243–1261
  15. Kaupe B, Brandt H, Prinzenberg EM, Erhardt G. Joint analysis of the influence of CYP11B1 and DGAT1 genetic variation on milk production, somatic cell score, conformation, reproduction, and productive lifespan in German Holstein cattle. J. Anim. Sci. 2007;85:11–21
  16. Komisarek J, Szyda J, Michalak A, Dorynek Z. Impact of leptin gene polymorphisms on breeding value for milk production traits in cattle. J. Anim. Feed Sci. 2005;14:491–500
  17. Konfortov BA, Licence VE, Miller JR. Re-sequencing of DNA from a diverse panel of cattle reveals a high level of polymorphism in both intron and exon. Mamm. Genome. 1999;10:1142–1145
  18. Kuehn C, Edel C, Weikard R, Thaller G. Dominance and parent-of-origin effects of coding and non-coding alleles at the acylCoA-diacylglycerol-acyltransferase (DGAT1) gene on milk production traits in German Holstein cows. BMC Genet. 2007;8:62
  19. Liefers SC, Veerkamp RF, te Pas MF, Delavaud C, Chilliard Y, van der Lende T. A missense mutation in the bovine leptin receptor gene is associated with leptin concentrations during late pregnancy. Anim. Genet. 2004;35:138–141
  20. Madeja Z, Adamowicz T, Chmurzynska A, Jankowski T, Melonek J, Switonski M, et al. Effect of leptin gene polymorphisms on breeding value for milk production traits. J. Dairy Sci. 2004;87:3925–3927
  21. Näslund J, Fikse WF, Pielberg GR, Lundén A. Frequency and effect of the bovine acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) K232A polymorphism in Swedish dairy cattle. J. Dairy Sci. 2008;91:2127–2134
  22. Sanders K, Bennewitz J, Reinsch N, Thaller G, Prinzenberg E-M, Kühn C, et al. Characterization of the DGAT1 mutations and the CSN1S1 promoter in the German Angeln dairy cattle population. J. Dairy Sci. 2006;89:3164–3174
  23. Schwarz G. Estimating the dimension of a model. Ann. Stat. 1978;6:461–464
  24. Seefried, F. R. 2008. Genomic characterisation and polymorphism analysis of candidate genes for milk production traits and association studies in three cattle breeds. PhD Thesis. Fakultät Wissenschaftszentrum Weihenstephan, Technische Universität München, Germany.
  25. Spelman RJ, Ford CA, Mcelhinney P, Gregory GC, Snell RG. Characterization of the DGAT1 gene in the New Zealand dairy population. J. Dairy Sci. 2002;85:3514–3517
  26. Suzuki R, Tobe K, Aoyama M, Sakamoto K, Ohsugi M, Kamei N, et al. Expression of DGAT2 in white adipose tissue is regulated by central leptin action. J. Biol. Chem. 2005;280:3331–3337
  27. Taylor C, Everest M, Smith C. Restriction fragment length polymorphism in amplification products of the bovine butyrophilin gene: Assignment of bovine butyrophilin to bovine chromosome 23. Anim. Genet. 1996;27:183–185
  28. Thaller G, Krämer W, Winter A, Kaupe B, Erhardt G, Fries R. Effects of DGAT1 variants on milk production traits in German cattle breeds. J. Anim. Sci. 2003;81:1911–1918
  29. Winter A, Krämer W, Werner FAO, Kollers S, Kata S, Durstewitz G, et al. Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content. Proc. Natl. Acad. Sci. USA. 2002;99:9300–9305
  30. Zeng ZB, Wang T, Zou W. Modelling quantitative trait loci and interpretation of models. Genetics. 2005;169:1711–1725

PII: S0022-0302(10)00275-4

doi: 10.3168/jds.2009-2550

Journal of Dairy Science
Volume 93, Issue 6 , Pages 2703-2717 , June 2010

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