Journal of Dairy Science
Volume 93, Issue 9 , Pages 3931-3939 , September 2010

Self-assembled β-lactoglobulin–conjugated linoleic acid complex for colon cancer-targeted substance

Received 10 January 2010 ,Accepted 28 March 2010.

References 

  1. ASTM (American Society for Testing and Materials).. Standard test methods for zeta potential of colloids in water and waste water. ASTM Standard D 4182–82. Annual Book of ASTM Standards. West Conshohocken, PA: ASTM International; 1985;
  2. Beppu F, Hosokawa M, Tanaka L, Kohno H, Tanaka T, Miyashita K. Potent inhibitory effect of trans9, trans11 isomer of conjugated linoleic acid on the growth of human colon cancer cells. J. Nutr. Biochem. 2006;17:830–836
  3. Bernasconi E, Fritsché R, Corthésy B. Specific effects of denaturation, hydrolysis and exposure to Lactococcus lactis on bovine β-lactoglobulin transepithelial transport, antigenicity and allergenicity. Clin. Exp. Allergy. 2006;36:803–814
  4. Brownlow S, Cabral JHM, Cooper R, Flower DR, Yewdall SJ, Polikarpov I, et al. Bovine β-lactoglobulin at 1.8 Å resolution—Still an enigmatic lipocalin. Structure. 1997;5:481–495
  5. Center MM, Jemal A, Smith RA, Ward E. Worldwide variations in colorectal cancer. CA Cancer J. Clin. 2009;59:366–378
  6. Chobert JM, Briand L, Grinberg V, Haertlé T. Impact of esterification on the folding and the susceptibility to peptic proteolysis of β-lactoglobulin. Biochim. Biophys. Acta. 1995;1248:170–176
  7. Christiaens B, Symoens S, Vanderheyden S, Engelborghs Y, Joliot A, Prochiantz A. Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes. Eur. J. Biochem. 2002;269:2918–2926
  8. Considine T, Patel HA, Singh H, Creamer LK. Influence of binding conjugated linoleic acid and myristic acid on the heat- and high-pressure-induced unfolding and aggregation of β-lactoglobulin B. Food Chem. 2007;102:1270–1280
  9. During A, Harrison EH. An in vitro model to study the intestinal absorption of carotenoids. Food Res. Int. 2005;38:1001–1008
  10. Flower DR. The lipocalin protein family: A role in cell regulation. FEBS Lett. 1994;354:7–11
  11. Frapin D, Dufour E, Haertle T. Probing the fatty-acid-binding site of beta-lactoglobulins. J. Protein Chem. 1993;12:443–449
  12. Futterman S, Heller J. The enhancement of fluorescence and the decreased susceptibility to enzymatic oxidation of retinol complexed with bovine serum albumin, lactoglobulin and the retinol-binding protein of human plasma. J. Biol. Chem. 1972;247:5168–5172
  13. Ha YL, Grimm NK, Pariza MW. Anticarcinogens from fried ground beef: Heat-altered derivatives of linoleic acid. Carcinogenesis. 1987;8:1881–1887
  14. Harvey BJ, Bell E, Brancaleon L. A tryptophan rotamer located in a polar environment probes pH-dependent conformational changes in bovine β-lactoglobulin A. J. Phys. Chem. B. 2007;111:2610–2620
  15. Kawaguchi R, Yu J, Honda J, Hu J, Whitelegge J, Ping P, et al. A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science. 2007;315:820–825
  16. Kay JK, Macle TR, Auldist MJ, Thomson NA, Bauman DE. Endogenous synthesis of cis-9, trans-11 conjugated linoleic acid in dairy cows fed fresh pasture. J. Dairy Sci. 2004;87:369–378
  17. Kelley NS, Hubbard NE, Erickson KL. Conjugated linoleic acid isomers and cancer. J. Nutr. 2007;137:2599–2607
  18. Kiabatake N, Kinekawa YI. Digestibility of bovine milk whey protein and β-lactoglobulin in vitro and in vivo. J. Agric. Food Chem. 1998;46:4917–4923
  19. Kontopidis G, Holt C, Sawyer L. β-Lactoglobulin: Binding properties, structure and function. J. Dairy Sci. 2004;87:785–796
  20. Konuma T, Sakurai K, Goto Y. Promiscuous binding of ligands by β-lactoglobulin involves hydrophobic interactions and plasticity. J. Mol. Biol. 2007;368:209–218
  21. Li Z, Gu T, Kelder B, Kopchick JJ. Analysis of fatty acids in mouse cells using reversed-phase high-performance liquid chromatography. Chromatography A. 2001;54:463–467
  22. Liu HC, Chen WL, Mao SJT. Antioxidant nature of bovine milk β-lactoglobulin. J. Dairy Sci. 2007;90:547–555
  23. McKenzie HA. β-Lactoglobulins. In:  McKenzie HA editors. Milk Proteins. London, UK.: Academic Press Inc. Ltd.; 1971;p. 2257–2330
  24. Palombo JD, Ganguly A, Birstrian BR, Menard MP. The antiproliferative effects of biologically active isomers of conjugated linoleic acid on human colorectal and prostatic cancer cells. Cancer Lett. 2002;177:163–172
  25. Papiz MZ, Sawyer L, Eliopoulos EE, North ACT, Findlay JBC, Sivaprasadarao R. The structure of β-lactoglobulin and its similarity to plasma retinol-binding protein. Nature. 1986;324:383–385
  26. Parkin DM, Bray FJ, Pisani P. Global cancer statistics. 2002. CA Cancer J. Clin. 2005;55:74–108
  27. Parodi PW. Cow's milk fat components as potential anticarcinogenic agents. J. Nutr. 1997;127:1055–1060
  28. Pérez MD, Calvo M. Interaction of β-lactoglobulin with retinol and fatty acids and its role as a possible biological function for this protein: A review. J. Dairy Sci. 1995;78:987–988
  29. Pervaiz S, Brew K. Homology of β-lactoglobulin, serum retinol-binding protein and protein HC. Science. 1985;228:335–337
  30. Ragona L, Fogolari F, Zetta L, Pérez DM, Puyol P, Kruif KD, et al. Bovine β-lactoglobulin: Interaction studies with palmitic acid. Protein Sci. 2000;9:1347–1356
  31. Reddy M, Kella NKD, Kinsella JE. Structural and conformational basis of the resistance of β-lactoglobulin to peptic and chymotryptic digestion. J. Agric. Food Chem. 1998;36:737–741
  32. Sundaram M, Sivaprasadarao A, DeSousa MM, Findlay JBC. The transfer of retinol from serum retinol-binding protein to cellular retinol-binding protein is mediated by a membrane receptor. J. Biol. Chem. 1999;273:3336–3342
  33. Wu SY, Pérez MD, Puyol P, Sawyer L. β-lactoglobulin binds palmitate within its central cavity. J. Biol. Chem. 1999;274:170–174
  34. Yamasaki M, Chujo H, Koga Y, Oishi A, Rikimaru T, Shimada M, et al. Potent cytotoxic effect of the trans10, cis12 isomer of conjugated linoleic acid on rat hepatoma dRLh-84 cells. Cancer Lett. 2002;188:171–180
  35. Zhao XL, Li KX, Zhao XF, Chen DW. Study on colon-specific 5-Fu pH-enzyme Di-dependent chitosan microspheres. Chem. Pharm. Bull. (Tokyo). 2008;56:963–968
  36. Zimet P, Livney YD. Beta-lactoglobulin and its nanocomplexes with pectin as vehicles for ω-3 polyunsaturated fatty acids. Food Hydrocoll. 2009;23:1120–1126

PII: S0022-0302(10)00417-0

doi: 10.3168/jds.2010-3071

Journal of Dairy Science
Volume 93, Issue 9 , Pages 3931-3939 , September 2010

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