Journal of Dairy Science
Volume 93, Issue 2 , Pages 437-455, February 2010

Invited review: Physiological properties of bioactive peptides obtained from whey proteins

Centro de Biotecnologia e Quımica Fina (CBQF)/Escola Superior de Biotecnologia, Universidade Católica Portuguesa, R. Dr. António Bernardino de Almeida, P-4200-072 Porto, Portugal

Received 14 July 2009; accepted 18 September 2009.

Abstract 

Processing of whey proteins yields several bioactive peptides that can trigger physiological effects in the human body: on the nervous system via their opiate and ileum-contracting activities; on the cardiovascular system via their antithrombotic and antihypertensive activities; on the immune system via their antimicrobial and antiviral activities; and on the nutrition system via their digestibility and hypocholesterolemic effects. The specific physiological effects, as well the mechanisms by which they are achieved and the stabilities of the peptides obtained from various whey fractions during their gastrointestinal route, are specifically discussed in this review.

Key words: whey, bovine, peptide, bioactivity

 

PII: S0022-0302(10)71487-9

doi:10.3168/jds.2009-2566

Journal of Dairy Science
Volume 93, Issue 2 , Pages 437-455, February 2010