Advertisement
Research-Article| Volume 65, ISSUE 9, P1765-1770, September 1982

Download started.

Ok

Absorption of Colostral Immunoglobulin G in the Newborn Dairy Calf1

Open ArchiveDOI:https://doi.org/10.3168/jds.S0022-0302(82)82414-4
Absorption of Colostral Immunoglobulin G in the Newborn Dairy Calf1
Previous ArticleAvailability of Macroelements from a Concentrate Diet Supplemented with Soybean Meal or Poultry Manure Fed to Sheep
Next ArticleRelationships Among Udder Depth, Hip Height, Hip Width, and Daily Milk Production in Holstein Cows
      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Five groups of eight newborn calves were used to study absorption of colostral immunoglobulin G. One feeding of 2 liters of pooled colostrum was given at one of 6, 12, 24, 36, or 48 h after birth. Concentrations of immunoglobulin G in blood plasma and feces were measured by an immunodiffusion technique. Plasma volume and fecal excretion also were measured. When colostrum was given 6 h after birth, 65.8% of the ingested immunoglobulin G appeared in the plasma. This percentage declined rapidly to reach 46.9%, 11.5%, 6.7%, and 6.0% when colostrum was given at the ages of 12, 24, 36, and 48 h. Total fecal immunoglobulin G increased linearly with age. The quantities not recovered from plasma and feces reached a maximum when colostrum was given at 24 or 36 h after birth. Immunoglobulin G can be “lost” to a great extent via routes other than plasma and feces during this time. Quantities of immunoglobulin G measured in plasma represent apparent rather than true absorption.

      References

        • Balfour W.E.
        • Comline R.S.
        Acceleration of the absorption of unchanged globulin in the newborn calf by factors in colostrum.
        J. Physiol. 1962; 160: 234
        • Bush L.J.
        • Staley T.E.
        Absorption of colostral immunoglobulins in newborn calves.
        J. Dairy Sci. 1980; 63: 672
        • Bush L.J.
        • Mungle M.B.
        • Corley L.D.
        • Adams G.D.
        Factors affecting absorption of immunoglobulins by newborn calves.
        J. Dairy Sci. 1973; 56: 512
        • Comline R.S.
        • Roberts H.E.
        • Titchen D.A.
        Route of absorption of colostrum globulin in the newborn animal.
        Nature. 1951; 167: 561
        • Devery J.E.
        • Davis C.L.
        • Larson B.L.
        Endogenous production of immunoglobuiins IgG1in newborn calves.
        J. Dairy Sci. 1979; 62: 1814
        • El Nageh M.M.
        Voies d’absorption des gamma-globulines du colostrum au niveau de 1’intestin grêle du veau nouveau-né.
        Ann. Méd. Vet. 1967; 111: 384
        • Husband A.J.
        • Brandon M.R.
        • Lascelles A.K.
        Absorption and endogenous production of immunoglobulins in calves.
        Australian J. Exp. Biol. Med. Sci. 1972; 50: 491
        • Husband A.J.
        • Brandon M.R.
        • Lascelles A.K.
        The effect of corticosteroid on absorption and endogenous production of immunoglobulins in calves.
        AJEBAK. 1973; 51: 501
        • Kickhöfen B.
        • Hammer D.K.
        • Westphal M.
        Occurrence of IgG fragments in the urine of the newborn calf.
        Eur. J. Immunol. 1971; 1: 49
        • Kruse V.
        Absorption of immunoglobulins from colostrum in newborn calves.
        Anim. Prod. 1970; 12: 627
        • Kruse V.
        Proteolysis, absorption and excretion of immunoglobulin IgG1 in newborn calves.
        K. Vet. Landbohojsk. Arsskr. 1973; : 173
        • Logan E.F.
        • Penhale W.J.
        Studies on the immunity of the calf to colibacillosis.
        Vet. Rec. 1972; 91: 419
        • Logan E.F.
        • Stenhouse A.
        • Arnold D.J.
        • Penhale W.J.
        The role of colostral immunoglobulin in intestinal immunity to enteric colibacillosis in the calf.
        Res. Vet. Sci. 1974; 17: 290
        • MacDougall D.F.
        • Mulligan W.
        The distribution and metabolism of fast IgG immunoglobulin in the neonatal calf.
        J. Physiol. Lond. 1969; 201: 77
        • McEwan A.D.
        • Fisher E.W.
        • Selman I.E.
        The effect of colostrum on the volume and composition of the plasma of the calves.
        Res. Vet. Sci. 1968; 9: 284
        • McEwan A.D.
        • Fisher E.W.
        • Selman I.E.
        An estimation of the efficiency of the absorption of immune globulin from colostrum by newborn calves.
        Res. Vet. Sci. 1970; 11: 239
        • Pierce A.E.
        Studies on the proteinuria of the newborn calf.
        J. Physiol. 1959; 148: 469
        • Saskai M.
        • Davis C.L.
        • Larson B.L.
        Immunoglobulin IgG1 metabolism in newborn calves.
        J. Dairy Sci. 1977; 60: 623
        • Shannon A.D.
        • Lascelles A.K.
        Lymph flow and protein composition of thoracic duct lymph in the newborn calf.
        J. Exp. Physiol. 1968; 53: 415
        • Snedecor G.W.
        • Cochran W.G.
        Méthodes statistiques.
        Assoc. Coord. Tech. Agri, Paris1957 (French trans. Statistical Methods. 6th ed. Iowa State Univ. Press, Ames.)
        • Steck F.T.
        Die Übertragung von Gamma-globulinen auf das neugeborene Kalb mit dem Colostrum.
        Schweiz. Arch. Furkeilkd. 1962; 104: 525
        • Stone S.S.
        • Deyoe B.L.
        Appearance of Brucella specific immunoglobulins in synovia of neonatal calves after colostrum feeding.
        Am. J. Vet. Res. 1974; 35: 1259
        • Stott G.H.
        • Marx D.B.
        • Menefee B.E.
        • Nightengale G.T.
        Colostral immunoglobulin transfer in calves. I. Period of absorption.
        J. Dairy Sci. 1979; 62: 1632

      Article info

      Publication history

      Received: August 13, 1981

      Identification

      DOI: https://doi.org/10.3168/jds.S0022-0302(82)82414-4

      Copyright

      © 1982 American Dairy Science Association. Published by Elsevier Inc.

      User license

      Elsevier user license |
      How you can reuse Information Icon
      Elsevier user license

      Permitted

      For non-commercial purposes:

      • Read, print & download
      • Text & data mine
      • Translate the article

      Not Permitted

      • Reuse portions or extracts from the article in other works
      • Redistribute or republish the final article
      • Sell or re-use for commercial purposes

      Elsevier's open access license policy

      ScienceDirect

      Access this article on ScienceDirect

      The content on this site is intended for healthcare professionals.


      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties.


      RELX