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Article| Volume 76, ISSUE 10, P3143-3159, October 1993

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Challenges to Dairy Cattle Management: Genetic Considerations1

Open ArchiveDOI:https://doi.org/10.3168/jds.S0022-0302(93)77654-7
Challenges to Dairy Cattle Management: Genetic Considerations1
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      Abstract

      Several new technologies will be used to produce continued genetic change in dairy cattle. These technologies are categorized broadly as 1) improved modeling, selection, and evaluation methods; 2) use of new and improved reproductive technologies; 3) new developments in molecular genetics; and 4) new developments in immunogenetics. Improvements in evaluation will continue as computers become faster and have more storage capabilities. Improved mathematical models that more nearly describe the biology of lactation will maximize estimation of genetic differences and reduce residuals. New reproductive technology could allow reduction of generation intervals two-to fivefold compared with present generation intervals and, combined with genetic markers, could markedly accelerate progress. Health problems in dairy cattle are expected to increase as production increases. Thus, selection for decreased incidences of health disorders will be needed, probably by selection of sires with improved general immunocompe-tence. Research is in the early stages of application of techniques of molecular genetics to animal breeding. Early uses will allow detection and alleviation of genetic defects. Eventually, marker genes that directly affect production and metabolic pathways that also affect production will be subjected to selection. The ability to foresee new and potentially useful techniques will be determined by scientific advancement of areas in which researchers are engaged; thus, accurate prediction far into the future cannot be expected.

      Key words

      Abbreviation key:

      BOLA (bovine lymphocyte antigen), ET (embryo transfer), MOET (multiple ovulation and embryo transfer)

      References

        • Almlid T.
        Indirect selection of bulls for improved resistance to disease in cattle.
        Livest. Prod. Sci. 1981; 8: 321
        • Angel P.
        • Karin M.
        The role of Jun, Fos, and the AP-1 complex in cell-proliferation and transformation.
        Biochim. Biophys. Acta. 1991; 1072: 129
        • Association of American Veterinary Medical Colleges Council of Deans
        Report of a workshop on animal health research in American agricultural research.
        Winrock Int. Conf. Ctr., Petit Jean Mountain, Morrilton, AR1984
        • Beerepoot G.M.M.
        • Freeman A.E.
        • Detilleux J.C.
        Effect of season, genetic line, and sire on growth concentrations of somatotropin in serum of Holstein cows in early lactation.
        J. Dairy Sci. 1991; 74: 3202
        • Bell S.P.
        • Learned R.M.
        • Jantzen H.-M.
        • Tjian R.
        Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis.
        Science (Washington, DC). 1988; 241: 1192
        • Biozzi G.
        • Mouton D.
        • Saut ‘Anna O.A.
        • Passos H.C.
        • Gennari M.
        • Reis M.H.
        • Ferreira V.C.A.
        • Heumann A.M.
        • Bouthillier Y.
        • Ibanez O.H.
        • Stiffel C.
        • Siqueira M.
        Genetics of immuno responsiveness to natural antigens in the mouse.
        Curr. Top. Microbiol. Immunol. 1979; 85: 31
        • Burnside E.B.
        • Meyer K.
        Potential impact of bovine somatotropin on dairy sire evaluation.
        J. Dairy Sci. 1988; 71: 2210
        • Cheng S.
        • Rothschild M.F.
        • Lamont S.J.
        Estimates of quantitative genetic parameters of immunological traits in chickens.
        Poult. Sci. 1991; 70: 2023
        • Christensen L.G.
        Use of embryo transfer in future cattle breeding schemes.
        Theriogenology. 1991; 35: 141
        • Christensen L.G.
        • Liboriussen T.
        Embryo transfer in the genetic improvement of dairy cattle.
        in: Smith C.J. McKay W.B. Exploiting New Technology in Animal Breeding. Oxford Univ. Press, New York, NY1986: 23
        • Collean J.J.
        Efficacite génétique du transfert d’embryons dans les noyaux de sélection chez les bovins laiters.
        Genet. Sel. Evol. 1985; 17: 499
        • Collean J.J.
        Genetic improvement by embryo transfer within open selection nucleus in dairy cattle.
        in: Proc. 3rd World Congr. Genet. Appl. Livest. Prod, Lincoln, NE1986: 127 (XII)
        • Cowan C.M.
        • Dentine M.R.
        • Ax R.L.
        • Schuler L.A.
        Structural variation around prolactin gene linked to quantitative traits in an elite Holstein sire family.
        Theor. Appl. Genet. 1990; 79: 577
        • Curran S.
        Fetal sex determination in cattle and horses by ultrasonography.
        Theriogenology. 1992; 37: 17
        • Dekkers J.C.M.
        • Shook G.E.
        Genetic and economic evaluation of nucleus breeding schemes for commercial artificial insemination firms.
        J. Dairy Sci. 1990; 73: 1926
        • Dennis J.A.
        • Healy P.J.
        • Bandet A.L.
        • O’Brien W.E.
        Molecular definition of bovine argininosuccinate synthetase deficiency.
        Proc. Natl. Acad. Sci. USA. 1989; 86: 7947
        • Ebert K.M.
        • Selgrath J.P.
        Changes in domestic livestock through genetic engineering.
        in: Pedersen R.A. McLaren A. First N.L. Current Communications in Cell and Molecular Biology. Cold Spring Harbor Laboratory Press, Plain view, NY1991: 233
        • First N.L.
        New advances in reproductive biology of gametes and embryos.
        in: Pedersen R.A. McLaren A. First N.L. Current Communications in Cell and Molecular Biology. Cold Spring Harbor Laboratory Press, Plainview, NY1991: 1
        • Freeman A.E.
        Genetic control of reproduction and lactation of dairy cattle.
        in: Proc. 3rd World Congr Genet. Appl. to Livest. Prod, Lincoln, NE1986: 3 (XII)
        • Hammer R.E.
        • Pursel V.G.
        • Rexroad C.E.
        • Wall R.J.
        • Bolt D.J.
        • Ebert K.M.
        • Palmiter R.D.
        • Brinster R.L.
        Production of transgenic rabbits, sheep and pigs by microinjection.
        Nature (Lond.). 1985; 315: 680
        • Harrison R.O.
        • Young J.W.
        • Freeman A.E.
        • Ford S.P.
        Effect of lactation level on reactivation of ovarian function, and intervals from parturition to first visual oestrus and conception in high-producing Holstein cows.
        Anim. Prod. 1989; 49: 23
        • Heer C.M.
        • Klaus I.M.
        • Bradley M.P.
        • Reed K.C.
        Rapid accurate sexing of livestock embryos.
        in: Proc. 4th World Congr. Genet. Appl. Livest. Prod, Edinburgh, Scotland1990: 334 (XVI)
        • Henderson C.R.
        A rapid method for computing the inverse of a relationship matrix.
        J. Dairy Sci. 1975; 58: 1727
        • Hoeschele I.
        • Meinert T.R.
        Association of genetic defects with yield and type traits: the weaver locus effect on yield.
        J. Dairy Sci. 1990; 73: 2503
        • Hutt F.B.
        Genetic indicators of resistance to disease in domestic animals.
        in: Proc. 1st World Congr. Genet. Appl. Livest. Prod, Madrid, Spain1974: 179 (11)
        • Jamieson A.
        The distribution of transferrin genes in cattle.
        Heredity. 1966; 21: 191
        • Jasper D.E.
        • McDonald J.S.
        • Mochrie R.D.
        • Philpot W.N.
        • Farmswoith R.J.
        • Spencer S.B.
        Bovine Mastitis Research: Needs, Funding, and Sources of Support, Natl. Mastitis Counc, Louisville, KY.
        Natl. Mastitis Counc, Arlington, VA1982
        • Joen G.L.
        • Mao I.L.
        • Jensen J.
        • Ferris T.A.
        Stochastic modeling of multiple ovulation and embryo transfer breeding schemes in small closed dairy populations.
        J. Dairy Sci. 1990; 73: 1938
        • Kehrli Jr., M.E.
        • Shuster D.E.
        • Ackerman M.R.
        Leukocyte adhesion deficiency among Holstein cattle.
        Cornell Vet. 1992; 82: 103
        • Kehrli Jr., M.E.
        • Weigel K.A.
        • Freeman A.E.
        • Thurston J.R.
        • Kelley D.H.
        Bovine sire effects on daughters’ in vitro blood neutrophil functions, lymphocyte blastogenesis, serum complement and conglutinin levels.
        Vet. Immunol. Immunopathol. 1991; 27: 303
        • Krizenbaum M.
        • Vaiman M.
        • Cotinot C.
        • Fellows M.
        PCR sexing bovine embryos using Y chromosome specific sequences.
        J. Cell Biochem. (Suppl.). 1989; 13E: 293
        • Landschulz W.
        • Johnson P.F.
        • McKnight S.L.
        The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.
        Science (Washington, DC). 1988; 240: 1759
        • Leipold H.W.
        • Dennis S.M.
        • Huston K.
        Syndactyly in cattle.
        Vet. Bull. 1973; 43: 399
        • Levings III, C.S.
        The Texas cytoplasm of maize: cytoplasmic male sterility and disease susceptibility.
        Science (Washington, DC). 1990; 250: 942
        • Lewin H.A.
        Disease resistance and immune response in cattle: strategies for the detection and evidence of their existence.
        J. Dairy Sci. 1989; 72: 1334
        • Lie Ø.
        Genetics of disease resistance.
        in: Proc. 4th World Congr. Genet. Appl. Livest. Prod, Edinburgh, Scotland1990: 421 (XVI)
        • Lyons D.T.
        • Freeman A.E.
        • Kuck A.
        Genetics of health traits in Holsteins.
        J. Dairy Sci. 1991; 74: 1092
        • McDaniel B.T.
        • Cassell B.G.
        Alternative uses of embryo transfer and their effect on rate of genetic changes.
        J. Dairy Sci. 1981; 64: 2484
        • McGrane M.M.
        • Yun J.S.
        • Patel Y.M.
        • Hanson R.W.
        Metabolic control of gene expression: in vivo studies with transgenic mice.
        Trends Biochem. Sci. 1992; 17: 40

      40. Miller, W. W. 1989. Comparison of genetic change in open and closed MOET breeding schemes. M.S. Thesis, Iowa State Univ., Ames.

        • Munkittrick T.W.
        • Nebel R.L.
        • Saacke R.G.
        Accessory sperm numbers for cattle inseminated with protamine sulfate microcapsules.
        J. Dairy Sci. 1992; 75: 725
        • Nicholas F.W.
        • Smith C.
        Increased rates of genetic change in dairy cattle by embryo transfer and splitting.
        Anim. Prod. 1983; 36: 341
        • Norman H.D.
        • Powell R.L.
        Genetic and economic change attained and possible.
        in: Van Horn H.H. Wilcox C.J. Large Dairy Herd Management. Symp. Am. Dairy Sci. Assoc, Champaign, IL1992: 59
        • Philpot W.N.
        Economics of mastitis control.
        Vet. Clin. North Am. Large Anim. Pract. 1984; 6: 223
        • Pieterse M.C.
        • Vos P.L.A.M.
        • Krup T.A.M.
        • Wurth Y.A.
        • van Beneden T.H.
        • Willemse A.H.
        • Taverne M.A.M.
        Transvaginal ultrasound guided follicular aspiration of bovine oocytes.
        Theriogenology. 1991; 35: 19
        • Pinder S.J.
        • Perry B.N.
        • Savva D.
        • Skidmore C.J.
        The polymerase chain reaction applied to identification of specific alleles of bovine milk protein genes.
        Biochem. Soc. Trans. 1990; 18: 675
        • Pitcovski J.
        • Heller D.E.
        Selection for early responsiveness of chickens for Escherichia coli and Newcastle disease virus.
        Poult. Sci. 1987; 66: 1276
        • Powell R.L.
        Possible rates of embryo transfers on evaluation of bulls and cows.
        J. Dairy Sci. 1981; 64: 2476
        • Prather R.S.
        • Robi J.M.
        Cloning by nuclear transfer and embryo splitting in laboratory and domestic animals.
        in: Pedersen R.A. McLaren A. First N.L. Current Communications in Cell and Molecular Biology. Cold Spring Harbor Laboratory Press, Plainview, NY1991: 205
        • Ptashne M.
        How transcriptional activators work.
        Nature (Lond.). 1988; 335: 683
        • Rommens J.M.
        • Iannuzzi M.C.
        • Kerem B.
        • Drumm M.L.
        • Melmer G.
        • Dean M.
        • Rozmahel R.
        • Cole J.L.
        • Kennedy D.
        • Hidaka N.
        • Zsiga M.
        • Buchwald M.
        • Riordan J.R.
        • Tsui L.-C.
        • Collins F.S.
        Identification of the cystic fibrosis gene: chromosome walking and jumping.
        Science (Washington, DC). 1989; 245: 1059
        • Ron M.
        • Genis I.
        • Ezra E.
        • Yoffe O.
        • Weller J.I.
        • Shani M.
        Mitochondrial DNA polymorphism and determination of effects on economic traits in dairy cattle.
        Anim. Biotechnol. 1992; 3: 201
        • Saeki K.
        • Hoshi M.
        • Leibfried-Rutledge M.L.
        • First N.L.
        In vitro fertilization and development in coculture.
        Theriogenology. 1991; 44: 256
        • Schrmtz F.
        • Everett R.W.
        • Quaas R.L.
        Herd-year-season clustering.
        J. Dairy Sci. 1991; 74: 629

      55. Schutz, M. M. 1991. Cytoplasmic and mitochondrial genetics effects on economic traits in dairy cattle Ph.D. Diss., Iowa State Univ., Ames.

        • Schutz M.M.
        • Freeman A.E.
        • Beitz D.C.
        • Mayfield J.E.
        The importance of maternal lineages on milk yield traits in dairy cattle.
        J. Dairy Sci. 1992; 75: 1331
        • Seely J.F.
        Large-sample properties of invariant quadratic unbiased estimators in the random one-way model.
        in: Proc. Conf. in Honor of C. R. Henderson. Variance Components Anim. Breed. July 16-17. Cornell Univ, Ithaca, NY1979: 189
        • Seidel Jr., G.E.
        Embryo transfer: the next 100 years.
        Theriogenology. 1991; 35: 171
        • Shamay A.
        • Pines M.
        • Waksman M.M.
        • Gertler A.
        Proliferation of bovine undifferentiated mammary epithelial cells in vitro is modulated by G-proteins.
        Mol. Cell. Endocrinol. 1990; 69: 217
        • Shanks R.D.
        • Bragg D.St.A.
        • Robinson J.L.
        Incidence and inheritance of deficiency for undine monophosphate synthase in Holstein bulls.
        J. Dairy Sci. 1987; 70: 1893
        • Shook G.E.
        Selection for disease resistance.
        J. Dairy Sci. 1989; 72: 1349
        • Singer M.
        • Berg P.
        Genes and Genomes.
        Univ. Science Books, Mill Valley, CA1991 (39)
        • Solbu H.
        • Lie Ø.
        Selection for disease resistance in dairy cattle.
        in: Proc. 4th World Congr. Genet. Appl. Livest. Prod, Edinburgh, Scotland1990: 445 (XVI)
        • Stanburg R.C.
        The Metabolic Basis of Inherited Disease.
        6th ed. McGraw-Hill, New York, NY1989
        • Stice S.L.
        Multiple generation bovine embryo cloning.
        in: Seidel G.E. Proc. Symp. Cloning Mammals by Nuclear Transplantation. Anim. Reprod. Biotech. Lab. Colorado State Univ, Fort Collins1992: 17
        • Teepker G.
        • Smith C.
        Combining clonal response and genetic response in dairy cattle improvement.
        Anim. Prod. 1989; 49: 163
        • Van Vleck L.D.
        Potential genetic impact of artificial insemination, sex selection, embryo transfer, cloning, and selfing in dairy cattle.
        in: Bracket B.J. Seidel Jr., G.E. Seidel S.M. New Technologies in Animal Breeding. Academic Press, Inc, New York, NY1981: 221
        • Van Vleck L.D.
        Contemporary groups for genetic evaluations.
        J. Dairy Sci. 1987; 70: 2456
        • von der Shams A.
        • van der Westerlaben L.A.J.
        • de Wit A.A.C.
        • Eyestone W.H.
        • de Boer H.A.
        Ultrasound-guided transvaginal collection of oocytes in the cow.
        Theriogenology. 1991; 35: 288
        • Wales Jr., T.P.
        Holstein-Friesian Herd Book.
        Egbort, Fidlar, and Chambers, Davenport, IA1885
        • Weigel K.A.
        • Freeman A.E.
        • Kehrli Jr., M.E.
        • Stear M.J.
        • Kelley D.H.
        Association of class I bovine lymphocyte antigen complex alleles with health and production traits in dairy cattle.
        J. Dairy Sci. 1990; 73: 2538
        • Weigel K.A.
        • Freeman A.E.
        • Kehrli Jr., M.E.
        • Thurston J.R.
        • Kelley D.H.
        Relationship of in vitro immune function with health and production in Holstein cattle.
        J. Dairy Sci. 1992; 75: 1672
        • Weigel K.A.
        • Kehrli Jr., M.E.
        • Freeman A.E.
        • Thurston J.R.
        • Stear M.J.
        • Kelley D.H.
        Association of class I bovine lymphocyte antigen complex alleles in vitro blood neutrophil functions, lymphocyte blastogenesis, serum complement and conglutinin levels in dairy cattle.
        Vet. Immunol. Immunopathol. 1991; 27: 321
        • Wiggans G.R.
        • Misztal I.
        • Van Vleck L.D.
        Implementation of an animal model for genetic evaluation of dairy cattle.
        J. Dairy Sci. 1988; 71: 54
        • Willadsen S.M.
        Cloning sheep and cow embryos.
        Genome. 1989; 31: 956
        • Wilson J.M.
        • Johnston D.E.
        • Jefferson D.M.
        • Mulligan R.C.
        Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.
        Proc. Natl. Acad. Sci. USA. 1988; 85: 4421
        • Wright G.
        • Carver A.
        • Cottom D.
        • Reeves D.
        • Scott A.
        • Simons P.
        • Wilmut I.
        • Garner I.
        • Colman A.
        High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep.
        Bio Technology. 1991; 9: 830
        • Wu G.Y.
        • Wu C.H.
        Receptor-mediated gene delivery and expression in vivo.
        J. Biol. Chem. 1988; 263: 14621

      Article info

      Publication history

      Accepted: December 14, 1992
      Received: June 22, 1992

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      DOI: https://doi.org/10.3168/jds.S0022-0302(93)77654-7

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      © 1993 American Dairy Science Association. Published by Elsevier Inc.

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