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Article| Volume 79, ISSUE 5, P886-894, May 1996

Effect of a Whey Protein Concentrate Used as a Colostrum Substitute or Supplement on Calf Immunity, Weight Gain, and Health

Open ArchiveDOI:https://doi.org/10.3168/jds.S0022-0302(96)76437-8
Effect of a Whey Protein Concentrate Used as a Colostrum Substitute or Supplement on Calf Immunity, Weight Gain, and Health
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      Abstract

      The efficacy of a whey protein concentrate was evaluated as a colostrum substitute or supplement in two experiments using four groups of 29 calves. In Experiment 1, calves were fed either 2 L of pooled colostrum (group 1) or 500 g of whey protein concentrate (group 2). A mean total of 123.6 and 17.7 g of Ig was fed to calves in groups 1 and 2, respectively. Mean serum IgG, total protein, and globulin concentrations and Ig antibody activities to Escherichia coli K99 and rotavirus were significantly higher for calves in group 1 at 24 to 36 h and at 3 wk of age. Weight gain from birth to 3 wk of age was significantly lower for calves in group 2. The incidence of diarrhea was high but not different between treatments. The mortality rate (0 to 3 wk) was significantly higher for calves in group 2 (27.6%) than for calves in group 1 (3.4%). In Experiment 2, calves were fed either 2 L of pooled colostrum (group 3) or a solution of 1 L of pooled colostrum plus 500 g of whey protein concentrate (group 4). A mean total of 117.2 and 69.1 g of Ig was fed to calves in groups 3 and 4, respectively. Absorption rate of IgG was significantly lower for calves in group 4.
      Mean serum IgG, total protein, and globulin concentrations and Ig antibody activities to E. coli K99 and rotavirus were significantly higher for calves in group 3 at 24 to 36 h and at 3 wk of age. Mortality rate, BW gain, and incidence of diarrhea did not differ significantly between groups.

      Key words

      Abbreviation key:

      RV (rotavirus), TP (total protein), WPC (whey protein concentrate)

      References

        • Abel Francisco S.F.
        • Quigley III, J.D.
        Serum immunoglobulin concentrations after feeding maternal colostrum or maternal colostrum plus colostral supplement to dairy calves.
        Am. J. Vet. Res. 1993; 54: 1051

      2. Alton, G. G., L. M. Jones, and D. E. Pietz. 1975. Laboratory Techniques in Brucellosis. 2nd ed. World Health Org. Monogr. Series No. 55. World Health Org., Geneva, Switzerland.

      3. Andrews, A. H. 1990. Colostrum. Part of nature's survival kit. Feed Compounder 10:22.

      4. Bambauer, C. 1988. Zum Einsatz des Spezialfuttermittels Colostrx® bei neugeborener Kalbern. Tierarztl. Hochsch., Diss. Ludwig-Maximilians-Universitat, Munich, Germany.

      5. Beyer, C. 1988. Gesundheitszustand und Immunstatus neugeborener Kalber nach Gabe des Molkeneiweißpulvers Colostrx® Tierarztl. Hochsch., Diss. Hannover, Germany.

        • Chelack B.J.
        • Morley P.S.
        • Haines D.M.
        Evaluation of methods for dehydration of bovine colostrum for total replacement of normal colostrum in calves.
        Can. Vet. J. 1993; 34: 407
        • Fagan J.G.
        • Dwyer P.J.
        • Quinlan J.F.
        The diagnosis and occurrence of enteropathogens associated with calf diarrhoea in Ireland.
        Ir. Vet. J. 1994; 47: 313
        • Fahey F.L.
        • McKelvey E.M.
        Quantitative determination of serum immunoglobulins in antibody-agar plates.
        J. Immunol. 1965; 94: 84
        • Greene H.J.
        • Bakheit H.A.
        A study of the aetiology, epidemiology and control of diarrhoea in Ireland.
        Ir. Vet. J. 1984; 38: 63
        • Haines D.M.
        • Chelack B.J.
        • Naylor J.M.
        Immunoglobulin concentrations in commercially available colostrum supplements for calves.
        Can. Vet. J. 1990; 31: 36
        • Henriksen S.A.
        • Pohlenz J.F.L.
        Staining of cryp-tosporidia by a modified Ziehl-Neelsen technique.
        Acta Vet. Scand. 1981; 22: 594
        • Hunt E.
        • Van Camp S.D.
        • Fleming S.
        Developing technologies for prevention of bovine failure of passive transfer of antibody (FPTA).
        Bovine Pract. 1988; 23: 131
        • Kim J.W.
        • Schmidt F.W.
        Zur Frage der Absorption von Kolostralen Immunglobulinen durch das Kalb.
        Dtsch. Tierärztl. Wochenschr. 1983; 90: 283
        • Lester T.L.
        Bovine rotavirus.
        in: Howard J.L. Current Veterinary Therapy. W. B. Saunders Co., Philadelphia, PA1993: 439
        • Lopez J.W.
        • Allen S.D.
        • Mitchell J.
        • Quinn M.
        Rotavirus and cryptosporidium shedding in dairy calf feces and its relationship to colostrum immune transfer.
        J. Dairy Sci. 1988; 71: 1288
        • Martin S.W.
        • Meek A.H.
        • Willberg P.
        Veterinary Epidemiology. Principles and Methods.
        Iowa State Univ. Press, Ames1987

      17. McEnroe, M.A.M. 1989. Studies on antimicrobial proteins in bovine whey. M.S. Thesis. Natl. Univ. Dublin, Ireland.

        • Naylor J.M.
        • Kronfeld D.S.
        • Bech-Nielsen S.
        • Bartholomew R.C.
        Plasma total protein measurement for prediction of disease and mortality in calves.
        JAVMA (J. Am. Vet. Med. Assoc.). 1977; 171: 635
        • Perino L.J.
        • Sutherland R.L.
        • Woollen N.E.
        Serum γ-glutamyltransferase activity and protein concentration at birth and after suckling in calves with adequate and inadequate passive transfer of immunoglobulin G.
        Am. J. Vet. Res. 1993; 54: 56
        • Pickel M.
        • Beyer C.
        • Grunert E.
        • Trautwein G.
        Gesundheitszustand und Immunoglobulinstatus beim neuge-borenen Kalb nach Verabreichung des Molkeneiweißpulvers Colostrx®.
        Tieraerztl. Umsch. 1991; 46: 210
        • Roy J.H.B.
        Management of health.
        5th ed. The Calf. Vol. 1. Butterworths, London, England1990 (53)

      22. SAS® User's Guide: Statistics, Version 5 Edition. 1985. SAS Inst., Inc., Cary, NC.

        • Seymour W.H.
        • Nocek J.E.
        • English J.E.
        • Siciliano-Jones J.
        Effect of a whey protein concentrate (Colostrx®) and brewer's yeast-35 on health and performance of Holstein calves.
        J. Dairy Sci. 1989; 72 (Abstr.): 414

      24. Stott, G. H., and D. O. Lucas, inventors. 1987. Immunologically active whey fraction and recovery process. Eur. Pat. Appl. C1. No. A23 J 1/20.

        • Stott G.M.
        • Marx D.B.
        • Menefee B.E.
        • Nightengale G.T.
        Colostral immunoglobulin transfer in calves. III. Amount of absorption.
        J. Dairy Sci. 1979; 62: 1902
        • Stott G.M.
        • Marx D.B.
        • Menefee B.E.
        • Nightengale G.T.
        Colostral immunoglobulin transfer in calves. IV. Effect of suckling.
        J. Dairy Sci. 1979; 62: 1908
        • Trainin Z.
        • Ungar-Waron H.
        IgM in the bovine immune system and its relevance to disease.
        in: Butler J.E. Nielsen K. Duncan J.R. The Ruminant Immune System. Plenum Press, New York, NY1981: 169
        • White D.G.
        Colostral supplementation in ruminants.
        Compend. Contin. Educ. Pract. Vet. 1993; 15: 335
        • White D.G.
        • Wagstaff A.J.
        Colostrum supplements and substitutes.
        Vet. Rec. 1990; 1271: 483
        • Zaremba W.
        • Guterbock W.M.
        • Holmberg C.A.
        Efficacy of a dried colostrum powder in the prevention of disease in neonatal Holstein calves.
        J. Dairy Sci. 1993; 76: 831

      Article info

      Publication history

      Accepted: January 9, 1996
      Received: May 17, 1995

      Identification

      DOI: https://doi.org/10.3168/jds.S0022-0302(96)76437-8

      Copyright

      © 1996 American Dairy Science Association. Published by Elsevier Inc.

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